AMURT arrived in Nigeria in 2010. Ebonyi State was selected as the first project area because of its high rates of maternal and infant mortality. The project is run in collaboration with the Ebonyi State government. As of August 2019, AMURT was present in five Local Government Areas in Ebonyi - Abakaliki, Ikwo, Ohaukwu, Onicha and Ebonyi. They currently partner with ten primary health facilities in the five LGAs in Ebonyi State. AMURT's focus is to extend primary healthcare and care for mothers and newborns to remote rural areas that previous had no access to health facilities. According to the organization, AMURT receives applications from rural communities, and new project areas are selected based on need and local community commitment. Community participation is at the heart of the strategy. Local health workers are given priority in recruitment. Delivery is free for women from the project area (A project area is the same as the ward, or in some cases, about 20 villages that make up the catchment area for the health center). AMURT also provides emergency assistance, when lives are in the balance for emergency obstetric, pediatric and newborn emergencies.

The network was set up in 2010 under the Women’s Health Project, providing family planning services through a network of privately owned hospitals. However, from 2013, the network expanded its scale to recruit more privately owned hospitals, maternities, pharmacies and patent proprietary medicine vendors (PPMVs) located in urban, semi-urban and rural areas. In addition the network supports the providers in provision of quality health care services (through capacity building, commodity supply and quality improvement initiatives), facilitation of medical credit fund by making the facilities bankable and demand generation through strategic behavioral change communication activities. Presently, the network comprises of 340 hospitals and clinics, 195 pharmacies and 185 PPMVs across 22 states of the federation. There was also an expansion in the scope of services. Presently, the network operates as a social franchise to provide quality services in the areas of family planning (short and long acting), maternal and child health, including BEmONC services and safe motherhood, Integrated Management of Childhood Illnesses (IMCI), Post Abortion care services, HCT and STI management, Malaria services, Cervical Cancer screening and Preventative therapy, clean and safe water treatment, diarrhea prevention and treatment.

The CEMDOS Bill was signed into law to ensure accurate measurement of Maternal Mortality Ratio (MMR) in Ondo State, and it mandates reporting of a maternal death irrespective of where the death occurred.

The Maternal and Newborn Health Thematic Fund (MHTF) is UNFPA’s flagship programme for improving maternal and newborn health and well-being. It was launched in 2008 to boost global funding and attention to maternal health. In 2010, Nigeria joined the countries that received support from the Maternal Health Thematic Fund.

The USAID-funded Health Policy Project (HPP) in Nigeria strengthened the capacity of government and civil society actors to generate evidence, advocate, and foster institutional commitment for Family Planning/Reproductive Health.