In 2015, the National Population Commission through the Population Technical Working Group—with support from the Health Policy Project, funded by the U.S. Agency for International Development (USAID)— conducted an implementation assessment of the policy. Responses included: (1) Nearly two-thirds of respondents had never read any part of the policy itself, demonstrating a lack of familiarity with much of its content. Three quarters of interviewees rated themselves as having little to no NPP content knowledge. (2) The majority of interviewees believed that the goals, objectives, and targets were not achievable within the 2004–2015 timeframe. Interviewees also stated that the lack of zonal or state disaggregation of targets impeded progress. In 2019, Dr Ghajji Bello, the Director General of the National Population Commission said that "the policy, if implemented, will result in improved maternal health and that of the newborn children."

Some of the projects results included: (1) The introduction and anchoring of quality assurance in ten selected hospitals (2) Achieving a reduction of maternal mortality in these hospitals by more than 50%; (3) The establishment of two specialized fistula wards (one per state) including rehabilitation facilities and provision of needed hospital equipment; 1,500 fistula patients were successfully treated (500 more than planned) and rehabilitated - many of them also got vocational training and microcredits to built up their own small businesses. (4) Seven doctors were trained as fistula surgeons and 15 ward nurses were trained in fistula care. (5) 43 doctors, 344 nurses and midwives, 200 CHEWS and 197 TBAs were trained on how to improve obstetric services in the ten selected hospitals. (6) Hospitals lacking theses facilities were provided with water and solar energy (satellite project); (7) 24,000 mosquito nets were provided to the selected hospitals and surrounding communities (satellite project) (8) 3,000 IUDs were distributed to the selected hospitals (donation from Bayer Schering) (9) TBAs were equipped with delivery kits and anti-shock garments (satellite project) (10) Hospitals were provided with drugs for Preventing Mother-to-Child Transmission (PMTCT) of HIV (donation from Boehringer Ingelheim).

According to a UNFPA report, In preparation for the Fistula Fortnight, twelve Nigerian doctors, forty nurses, forty social workers, and twenty Red Cross volunteers were trained in fistula management and counselling. The state governments of Kano, Katsina, Kebbi and Sokoto committed in 2004 to placing the trained nurses and doctors at the four fistula centres in which the Fortnight was to take place at the conclusion of their training in February 2005. Additionally, the state governments began facility renovations to strengthen the capacity of the centres in preparation for the Fortnight The report also stated that Nigeria received an estimated total of $180,949 USD in 2004 from the US Committee for UNFPA, UNFPA Core Resources and the Government of Finland for Campaign to End Fistula related activity.

According to Health Partners International, a major aspect of PRRINN-MNCH was to mitigate the weakness and fragmentation of the health system. To address this Primary Health Care Under One Roof (PHCUOR) was rolled out to enhance coordination, collaboration, effectiveness and efficiency as well as eliminating constraints, fragmentation, managerial uncertainty and wastage of resources. PHCUOR becoming national policy in 2011 and 23 states adopted the policy. PRRINN-MNCH also sought to improve access to financial resources in the health sector, which included major financing reforms with significant impact on government’s health budgeting and planning, particularly by bringing all financing under a single budget. To strengthen PHC delivery in Zamfara state a pooled fund (called the Basket Fund) was created. State, local government and development partners all contributed to the pool fund, which was used for tasks such as supervision, vaccine distribution and outreach services. PRRINN-MNCH rolled out the District Health Information Systems 2 (DHIS2) across implementation states, in collaboration with Health Information Systems Program – Nigeria (HISP Nigeria) and also successfully pioneered the use of the mobile version of the software. At the end of the project all four PRRINN-MNCH states were using DHIS2. PRRINN-MNCH developed and implemented a human resource information system (HRIS) that was used to capture baseline HR information, plan for equitable distribution of health workers within an affordable envelope and support administration of human resources. The HRIS empowered state managers to address problems such as ghost workers, absenteeism and maldistribution and shortage of health workers, especially female health workers. According to Transaid, the establishment of the Emergency Transport System in Katsina, Yobe, and Zamfara was done through PRRINN-MNCH.

The goal of the ACCESS/Nigeria Project was the same as that stated in the Federal Ministry of Health’s (FMOH) National Reproductive Health Policy – “to reduce maternal and neonatal mortality in Nigeria” - and “to accelerate the reduction of maternal and newborn mortality and the attainment of the Millennium Development Goals in Nigeria.” The ACCESS/Nigeria project approach for achieving this goal was through the implementation of integrated community and facility-based maternity and EmONC interventions including antenatal and postnatal care and FP, while ensuring a “household-to-hospital continuum of care” (HHCC). The ACCESS/Nigeria approach focused on increasing both the supply of and the demand for quality interventions.